Duspatal® (Duspatalin®, Colofac®) is available in 3 different presentation forms: 100 mg and 135 mg tablet, 200 mg capsule.
Not all presentation forms are available in all countries. For further information on Duspatal® in your country please visit the Local contacts.
Duspatal® is best taken 20 minutes before meals.
Presentation forms:
tablet :
as a tablet containing 100 or 135 mg mebeverine hydrochloride
the tablets are white, round and sugar coated
dosage 3 times 135 mg/day, 4 times 100 mg/day
capsule :
as a capsule containing 200 mg mebeverine hydrochloride in a prolonged release formulation the capsules are white
dosage: Twice 200 mg/day
dosage:
age of patient
dosage
3 times a day
3 years
2.5 ml = 7.5 ml per 24 hours
3 times a day
4 - 8 years
5.0 ml = 15 ml per 24 hours
3 times a day
9 - 10 years
10 ml = 30 ml per 24 hours
3 times a day
over 10 years
15 ml = 45 ml per 24 hours
Indications
Duspatal® is indicated for:
Symptomatic treatment of abdominal pain and cramps, bowel disturbances and intestinal discomfort related to IBS.
Treatment of gastrointestinal spasm secondary to organic disease.
Pharmacology
Duspatal® (mebeverine) is a musculotropic antispasmodic with a direct action on the smooth muscle of the gastrointestinal tract, relieving spasm without affecting normal gut motility. Since this action is not mediated by the autonomic nervous system, the usual anticholinergic side effects are absent.
Side-effects
Duspatal® does not act via the autonomic nervous system, so there are none of the usual anticholinergic side effects such as a dry mouth, blurred vision, urine retention, constipation and drowsiness.
For this reason, Duspatal® can be used for patients with prostatic hypertrophy, urinary retention or glaucoma.
Safety profile
Safety and tolerance data have been collected from clinical trials in which more than 3500 patients received Duspatal® (mebeverine).
In all studies Duspatal® (mebeverine) was very well tolerated. In very rare cases allergic reactions have been reported. For more detail see your national product description.
Product profile
Duspatal® is an effective drug for patients with IBS:
Eliminates pain
Relieves the bowels
Improves stool reliably
No anticholinergic side-effects
The prolonged release formulation (Duspatal® retard)
Sustained release without side-effects
200 mg in the morning, 200 mg at night and peace in between
Please choose the content of your interest
